The most well known treatment for erectile dysfunction, or ED, is Viagra and this medication has successfully treated millions of men. However, while the patent was still valid, it was previously unaffordable for many people. Fortunately, this medication has become affordable for an increasing number of men. The patent for this popular ED treatment expired in 2013 and reputable generic companies are now licensed to manufacture cost-effective sildenafil citrate tablets.
A dose-response study was conducted to assess the safety and efficacy of this medication in men with ED. Altogether, 532 men received 25mg, 50mg or sildenafil 100mg price effective tablets to take. The researchers used standardised questionnaires to determine results and found that higher doses were associated with better erectile function. One question asked the men how often they were able to achieve an erection. For the men using 100mg sildenafil, the answer to this question was 100% higher at the end of treatment compared to the beginning.
The smooth muscle cells that line the blood vessels of the penis contain especially high concentrations of an enzyme called PDE5. Sometimes, this enzyme is responsible for reducing the body’s ability to produce nitric oxide. Sildenafil 100mg price reduced tablets decrease the activity of PDE5. Nitric oxide production increases as a result and this causes blood vessels to become wider. Consequently, blood flow improves leading to firm and sustainable erections.
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