The efficacy of sildenafil has been proven in many clinical studies and patients usually start treatment at 50mg. For most men with erectile dysfunction (ED), 50mg provides worthwhile benefits. However, medical professionals usually agree that a higher dose provides superior results. Research took place to compare the efficacy between a 100mg dose and a 50mg dose.
Altogether, five studies were included with a total of more than 1,500 men who had ED for an average of 4.3 years. The men received at least one dose of placebo or a sildenafil dosage of 50mg or 100mg. The Erection Hardness Score (EHS) was used in the studies and this assessment tool enables men to score the hardness of their erections. It uses a score that ranges from 0 to 4, whereby 0 represents no erection and 4 shows a completely hard erection.
The study found that, compared to inactive placebo pills, the chance of achieving an EHS score of 4 was much higher for both doses of sildenafil. The researchers found that, in general, the chance of achieving an EHS score of 4 was also higher for the sildenafil dosage of 100mg compared to 50mg. In fact, in one of the studies, the chance of achieving an EHS score of 4 was nearly doubled for the men who took the higher dose.
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